个人介绍
陈雪瑞，2019年毕业于浙江大学获得理学博士学位，同年进入上海大学医学院任讲师。至今已在ACS Appl. Mater. Interfaces, Biomater. Sci., ACS Biomater. Sci. Eng., Langmuir, RSC Adv., Colloid. Surface. B., Colloid. Surface. A., Oncol. Rep.等SCI收录的期刊上发表10篇论文。主持一项国家自然科学青年基金。
主要研究领域
1.肿瘤微环境响应型纳米递药系统的构建与靶向功能修饰；
2.抗肿瘤药物的靶向释放与协同治疗；
3.生物热力学及微量热学。
代表性学术成果
论文
1.Chen, X.R.; Tong, R.L.; Shi, Z.Q.; Yang, B.; Liu, H.; Ding, S.P.; Wang, X.; Lei, Q.F.; Wu, J.*; Fang, W.J*. MOF Nanoparticles with Encapsulated Autophagy Inhibitor in Controlled Drug Delivery System for Antitumor.ACS Appl. Mater. Interfaces, 2018, 10 (3), 2328-2337.（高被引论文）
2.Chen, X.R.#; Tong, R.L.#; Liu, B.B.; Liu H.; Feng X.D.; Ding, S.P.; Lei, Q.F.; Tang, G.P.; Wu, J.*; Fang, W.J.*Duo of (–)-Epigallocatechin-3-Gallate and Doxorubicin Loaded by Polydopamine Coating ZIF-8 in Regulation of Autophagy for Chemo-Photothermal Synergistic Therapy.Biomater. Sci., 2020, 8(5), 1380-1393.
3.Chen, X.R.; Shi, Z.Q.; Tong, R.L.; Ding, S.P.; Wang, X.; Wu, J.; Lei, Q.F.*; Fang, W.J.*Derivative of Epigallocatechin-3-gallatea Encapsulated in ZIF-8 with Polyethylene Glycol–Folic Acid Modification for Target and pH-Responsive Drug Release in Anticancer Research.ACS Biomater. Sci. Eng.2018, 4 (12), 4183-4192.
4.Chen, X.R.; Zhang, L.; Ding, S.P.; Lei, Q.F.*; Fang, W.J.*Cisplatin Combination Drugs Induce Autophagy in HeLa Cells and Interact with HSA via Electrostatic Binding Affinity.RSC Adv., 2017, 7, 22270-22279.
5.Shi, Z.Q.;Chen, X.R.; Zhang, L.; Ding, S.P.; Wang, X.; Lei, Q.F.*; Fang, W.J.*FA-PEG Decorated MOF Nanoparticles as a Targeted Drug Delivery System for Controlled Release of an Autophagy Inhibitor.Biomater. Sci.2018, 6, 239-240.
6.Zhang, S.S.;Chen, X.R.; Yu, J.; Hong, B.Y.; Lei, Q.F.*; Fang, W.J.*Hydrophobic Fractal Surface from Glycerol Tripalmitate and the Effects on C6 Glioma Cell Growth.Colloid. Surface. B.2016, 142, 377-384.
7.Zhang, S.S.;Chen, X.R.; Ding, S.P.; Lei, Q.F.*; Fang, W.J.*Unfolding of Human Serum Albumin by Gemini and Single-chain Surfactants: A Comparative Study.Colloid. Surface. A.2016, 495, 30-38.
8.Zhang, L.;Chen, X.R.; Wu, J.Z.; Ding, S.P.; Wang, X.; Lei, Q.F*.; Fang, W.J.*Palladium Nanoparticles Induce Autophagy and Autophagic Flux Blockade in Hela Cells.RSC Adv., 2018, 8, 4130.
9.Chen, Y., Zhuang, H.F.,Chen, X. R., Shi, Z. Q., Wang, X.*, Spermidine-induced Growth Inhibition and Apoptosis via Autophagic Activation in Cervical Cancer.Oncol. Rep.2018, 39(6), 2845-2854.
10. Zhang, S.S.; Ding, S. P., Yu, J.;Chen, X.R.; Lei, Q.F.*; Fang, W.J.*Antibacterial Activity, in Vitro Cytotoxicity, and Cell Cycle Arrest of Gemini Quaternary Ammonium Surfactants.Langmuir, 2015, 31(44), 12161-12169.
